There was talk of removing a chicane some years back, In the end the drivers felt removing the 1st chicane would be too dangerous but quite a few were open to removing the 2nd chicane.
The issue with Grand-Curve without the 1st chicane is where the wall comes back towards the track at the exit. There was also the issue with the 2nd chicane with the increased speed, Not as much run-off there as you would need at 210-220mph.
Im also not sure it would work with F1 cars, With the low downforce package they run at Monza + DRS they would probably be on the Rev-limiter before they even got to Grand-Curve. They run there lowest downforce package & highest top gear’s at Monza currently & are often touching the limiter before turn 1 as it is.
LMP cars are designed around Le Mans so are designed to be doing 220mph+ down the Mulsanne straight. F1 cars are designed to work everywhere so there’s no way anyone would throw a significant amount of R&D developing a super low-aero package/much taller gear ratio package specifically for a chicane-less Monza.